Cyclobenzaprine oral tablet comes with several important warnings.
- Serotonin syndrome warning: This drug can cause a life threatening condition called serotonin syndrome. This happens when medications cause too much serotonin to build up in your body. Call your doctor right away if you have any symptoms of this condition. These include agitation (a feeling of aggravation or restlessness), hallucinations (seeing or hearing something that isn’t there), seizures, or nausea. Your risk may be higher if you take cyclobenzaprine with other drugs that increase the risk of serotonin syndrome, such as antidepressants.
- Effects on the heart warning: This drug may cause heart arrhythmias (heart rate or rhythm problems). Your risk may be higher if you take a drug to treat depression or already have heart problems. If these issues are left untreated, they can lead to a heart attack or stroke.
- Central nervous system warning: This drug can cause drowsiness, dizziness, hallucinations (seeing or hearing things that aren’t there), and delusions (believing things that aren’t true). You should not drive or use machinery while you’re on this medication until you know how it affects you. Your risk may be higher if you’re 65 years or older.
Allergy warning
Cyclobenzaprine can cause an allergic reaction, which can be mild or severe. Symptoms can include:
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- trouble breathing
- swelling of your throat or tongue
For mild allergic reaction symptoms, such as a mild rash, call your doctor right away. They may recommend treatments to help manage your symptoms. They’ll also let you know whether you should keep taking the medication.
For severe allergic reaction symptoms, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms require immediate medical care because they can become life threatening. If you’ve had a serious allergic reaction to cyclobenzaprine, your doctor may recommend taking a different medication instead.
Alcohol interaction
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Using drinks containing alcohol can increase your risk of dizziness, drowsiness, and decreased alertness from cyclobenzaprine. If you drink alcohol, talk with your doctor.
Warnings for people with certain health conditions
For people with trouble urinating: This drug can make your symptoms worse.
For people with glaucoma: This drug can make your symptoms worse.
For people with liver problems: If you have liver problems or a history of liver disease, you may not be able to clear this drug from your body well. This may cause it to build up in your body. This raises your risk of side effects.
Warnings for other groups
For pregnant people: Speak with your doctor if you’re pregnant or planning to become pregnant.
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Research in animals has not shown a risk to the fetus when cyclobenzaprine is given to pregnant females. However, there aren’t enough studies done in humans to show if the drug poses a risk to the fetus.
Animal studies don’t always predict the way humans would respond. Therefore, you should only use this drug during pregnancy if it’s clearly necessary. Talk with your doctor about other medications that may be a better fit for you.
For people who are breastfeeding: Cyclobenzaprine may pass into breast milk and may cause side effects in a child who is breastfed. Talk with your doctor if you’re breastfeeding. Together, you may need to decide whether you should stop breastfeeding or stop taking this medication.
For older adults: The kidneys and liver of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of the drug stays in your body for longer. This raises your risk of side effects.
For children: Doctors won’t prescribe cyclobenzaprine oral tablet for use in people younger than age 15 years.
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