TEA TREE OIL – Uses, Side Effects, and More

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Brady, A., Loughlin, R., Gilpin, D., Kearney, P., and Tunney, M. In vitro activity of tea-tree oil against clinical skin isolates of meticillin-resistant and -sensitive Staphylococcus aureus and coagulase-negative staphylococci growing planktonically and as biofilms. J Med Microbiol. 2006;55(Pt 10):1375-1380. View abstract.

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Brand, C., Ferrante, A., Prager, R. H., Riley, T. V., Carson, C. F., Finlay-Jones, J. J., and Hart, P. H. The water-soluble components of the essential oil of Melaleuca alternifolia (tea tree oil) suppress the production of superoxide by human monocytes, but not neutrophils, activated in vitro. Inflamm.Res 2001;50(4):213-219. View abstract.

Caelli M and Riley T. Tea tree oil – an alternative topical decolonisation agent for adult inpatients with methicillin-resistant staphylococcus aureus (MRSA) – a pilot study. J Hosp Infect 1998;40 (Suppl A):9.

Carson, C. F. and Riley, T. V. Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia. J Appl Bacteriol. 1995;78(3):264-269. View abstract.

Carson, C. F., Hammer, K. A., and Riley, T. V. In-vitro activity of the essential oil of Melaleuca alternifolia against Streptococcus spp. J Antimicrob.Chemother 1996;37(6):1177-1178. View abstract.

Carson, C. F., Hammer, K. A., and Riley, T. V. Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clin Microbiol.Rev 2006;19(1):50-62. View abstract.

Concha, J. M., Moore, L. S., and Holloway, W. J. Antifungal activity of Melaleuca alternifolia (tea-tree) oil against various pathogenic organisms. J Am Podiatr.Med Assoc 1998;88(10):489-492. View abstract.

Cox, S. D., Gustafson, J. E., Mann, C. M., Markham, J. L., Liew, Y. C., Hartland, R. P., Bell, H. C., Warmington, J. R., and Wyllie, S. G. Tea tree oil causes K+ leakage and inhibits respiration in Escherichia coli. Lett Appl Microbiol 1998;26(5):355-358. View abstract.

Culliton, P. and Halcon, L. L. Chronic wound treatment with topical tea tree oil. Altern.Ther.Health Med. 2011;17(2):46-47. View abstract.

D’Auria, F. D., Laino, L., Strippoli, V., Tecca, M., Salvatore, G., Battinelli, L., and Mazzanti, G. In vitro activity of tea tree oil against Candida albicans mycelial conversion and other pathogenic fungi. J Chemother 2001;13(4):377-383. View abstract.

Gustafson, J. E., Liew, Y. C., Chew, S., Markham, J., Bell, H. C., Wyllie, S. G., and Warmington, J. R. Effects of tea tree oil on Escherichia coli. Lett.Appl Microbiol 1998;26(3):194-198. View abstract.

Hammer, K. A., Carson, C. F., and Riley, T. V. In vitro susceptibility of Malassezia furfur to the essential oil of Melaleuca alternifolia. J Med Vet Mycol. 1997;35(5):375-377. View abstract.

Hart, P. H., Brand, C., Carson, C. F., Riley, T. V., Prager, R. H., and Finlay-Jones, J. J. Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes. Inflamm.Res 2000;49(11):619-626. View abstract.

Hausen, B. M., Reichling, J., and Harkenthal, M. Degradation products of monoterpenes are the sensitizing agents in tea tree oil. Am J Contact Dermat. 1999;10(2):68-77. View abstract.

Kulik, E., Lenkeit, K., and Meyer, J. [Antimicrobial effects of tea tree oil (Melaleuca alternifolia) on oral microorganisms]. Schweiz Monatsschr.Zahnmed. 2000;110(11):125-130. View abstract.

Lee, G., Anand, S. C., and Rajendran, S. Are biopolymers potential deodourising agents in wound management? J Wound.Care 2009;18(7):290, 292-290, 295. View abstract.

Loughlin, R., Gilmore, B. F., McCarron, P. A., and Tunney, M. M. Comparison of the cidal activity of tea tree oil and terpinen-4-ol against clinical bacterial skin isolates and human fibroblast cells. Lett.Appl.Microbiol. 2008;46(4):428-433. View abstract.

McCage, C. M., Ward, S. M., Paling, C. A., Fisher, D. A., Flynn, P. J., and McLaughlin, J. L. Development of a paw paw herbal shampoo for the removal of head lice. Phytomedicine 2002;9(8):743-748. View abstract.

Millar, B. C. and Moore, J. E. Successful topical treatment of hand warts in a paediatric patient with tea tree oil (Melaleuca alternifolia). Complement Ther.Clin.Pract. 2008;14(4):225-227. View abstract.

Nenoff, P., Haustein, U. F., and Brandt, W. Antifungal activity of the essential oil of Melaleuca alternifolia (tea tree oil) against pathogenic fungi in vitro. Skin Pharmacol 1996;9(6):388-394. View abstract.

Peña EF. Melaleuca alternifolia oil. Its use for trichomonal vaginitis and other vaginal infections. Obstet Gynecol 1962;19(6):793-795.

Raman, A., Weir, U., and Bloomfield, S. F. Antimicrobial effects of tea-tree oil and its major components on Staphylococcus aureus, Staph. epidermidis and Propionibacterium acnes. Lett Appl Microbiol 1995;21(4):242-245. View abstract.

Reuter, J., Merfort, I., and Schempp, C. M. Botanicals in dermatology: an evidence-based review. Am J Clin Dermatol 2010;11(4):247-267. View abstract.

Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97. View abstract.

Schnitzler, P., Schon, K., and Reichling, J. Antiviral activity of Australian tea tree oil and eucalyptus oil against herpes simplex virus in cell culture. Pharmazie 2001;56(4):343-347. View abstract.

Sherry, E., Boeck, H., and Warnke, P. H. Percutaneous treatment of chronic MRSA osteomyelitis with a novel plant- derived antiseptic. BMC.Surg 2001;1(1):1. View abstract.

Takarada, K., Kimizuka, R., Takahashi, N., Honma, K., Okuda, K., and Kato, T. A comparison of the antibacterial efficacies of essential oils against oral pathogens. Oral Microbiol.Immunol 2004;19(1):61-64. View abstract.

Thompson, G., Blackwood, B., McMullan, R., Alderdice, F. A., Trinder, T. J., Lavery, G. G., and McAuley, D. F. A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin-resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol. BMC.Infect.Dis. 2008;8:161. View abstract.

Vazquez JA, Vaishampayan J, Arganoza MT, and et al. Use of an over the counter product, Breathaway (Melaleuca oral solution), as an alternative agent for refractory oropharyngeal candidiasis in AIDS patients [abstract]. Int Conf AIDS 1996;11:109.

Veal, L. The potential effectiveness of essential oils as a treatment for headlice, Pediculus humanus capitis. Complement Ther Nurs.Midwifery 1996;2(4):97-101. View abstract.

Williams LR, Home VN, Zhang X, and et al. The composition and bactericidal activity of oil of Melaleuca alternifolia (tea tree oil). Int J Aromather 1988;1:15-17.

Williamson, E. M., Priestley, C. M., and Burgess, I. F. An investigation and comparison of the bioactivity of selected essential oils on human lice and house dust mites. Fitoterapia 2007;78(7-8):521-525. View abstract.

Allen P. Tea tree oil: the science behind the antimicrobial hype. Lancet 2001;358:1245. View abstract.

Ambrogio F, Foti C, Cazzato G, et al. Spreading Allergic Contact Dermatitis to Tea Tree Oil in an Over-the-Counter Product Applied on a Wart. Medicina (Kaunas) 2022;58(5):561. View abstract.

Andersen LP, Holck S, Kupcinskas L, et al. Gastric inflammatory markers and interleukins in patients with functional dyspepsia treated with astaxanthin. FEMS Immunol.Med Microbiol. 2007;50:244-48. View abstract.

Arweiler NB, Donos N, Netuschil L, Reich E and Sculean A. Clinical and antibacterial effect of tea tree oil-a pilot study. Clin Oral Investig 2000;4(2):70-73. View abstract.

Barker SC and Altman PM. A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice in children-melaleuca oil and lavender oil, pyrethrins and piperonyl butoxide, and a “suffocation” product. BMC Dermatol 2010;10:6. View abstract.

Barker SC and Altman PM. An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application-melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil, and a “suffocation” pediculicide. BMC Dermatol 2011;11:14. View abstract.

Bassett IB, Pannowitz DL, Barnetson RS. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Aust 1990;153:455-8. View abstract.

Bekhof AMW, van Hunsel FPAM, van de Koppel S, Woerdenbag HJ. Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum). Phytother Res 2022. View abstract.

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Bhushan M, Beck MH. Allergic contact dermatitis from tea tree oil in a wart paint. Contact Dermatitis 1997;36:117-8. View abstract.

Blackwell AL. Tea tree oil and anaerobic (bacterial) vaginosis. Lancet 1991;337:300. View abstract.

Blackwood B, Thompson G, McMullan R, Stevenson M, Riley TV, Alderdice FA, Trinder TJ, Lavery GG, McAuley DF. Tea tree oil (5%) body wash versus standard care (Johnson’s Baby Softwash) to prevent colonization with methicillin-resistant Staphylococcus aureus in critically ill adults: a randomized controlled trial. J Antimicrob Chemother. 2013 May;68(5):1193-9. View abstract.

Bruynzeel DP. Contact dermatitis due to tea tree oil. Trop Med Int Health 1999;4:630. View abstract.

Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotimazole. J Fam Pract 1994;38:601-5. View abstract.

Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole. J Fam Pract 1994;38:601-5. View abstract.

Caelli M and Riley T. Tea tree oil – an alternative topical decolonisation agent for adult inpatients with methicillin-resistant staphylococcus aureus (MRSA) – a pilot study. J Hosp Infect 1998;40 (Suppl A):9.

Caelli M., Porteous J., Carson C. F., Heller R. and Riley T. V. Tea tree oil as an alternative topical decolonization agent for methicillin-resistant Staphylococcus aureus. J Hosp Infect 2000;46(3):236-237. View abstract.

Canyon DV and Speare R. A comparison of botanical and synthetic substances commonly used to prevent head lice (Pediculus humanus var. capitis) infestation. Int J Dermatol 2007;46(4):422-426. View abstract.

Carson C. F. and Riley T. V. Safety, efficacy and provenance of tea tree (Melaleuca alternifolia) oil. Contact Dermatitis 2001;45(2):65-67. View abstract.

Carson CF, Cookson BD, Farrelly HD, Riley TV. Susceptibility of methicillin-resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia. J Antimicrob Chemother 1995;35:421-4.. View abstract.

Carson CF, Riley TV, Cookson BD. Efficacy and safety of tea tree oil as a topical antimicrobial agent. J Hosp Infect 1998;40:175-8. View abstract.

Carson CF, Riley TV. The antimicrobial activity of tea tree oil. Med J Aust 1994;160:236. View abstract.

Carson CF, Riley TV. Toxicity of the essential oil of Melaleuca alternifolia or tea tree oil. J Toxicol Clin Toxicol 1995;33:193-4. View abstract.

Carson CR, Ashton L, Dry L, et al. Melaleuca alternifolia (tea tree) oil gel (6%) for the treatment of recurrent herpes labialis. J Antimicrob Chemother 2001;48:450-1. View abstract.

Catalan A, Pacheco JG, Martinez A and Mondaca MA. In vitro and in vivo activity of Melaleuca alternifolia mixed with tissue conditioner on Candida albicans. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105(3):327-332. View abstract.

Chan CH, Loudon KW. Activity of tea tree oil on methicillin-resistant Staphylococcus aureus (MRSA). J Hosp Infect 1998;39:244-5. View abstract.

Christoffers WA, Blömeke B, Coenraads PJ, Schuttelaar ML. Co-sensitization to ascaridole and tea tree oil. Contact Dermatitis. 2013 Sep;69(3):187-9. View abstract.

Corazza M, Borghi A, Gallo R, Schena D, Pigatto P, Lauriola MM, Guarneri F, Stingeni L, Vincenzi C, Foti C, Virgili A. Topical botanically derived products: use, skin reactions, and usefulness of patch tests. A multicentre Italian study. Contact Dermatitis. 2014 Feb;70(2):90-7. View abstract.

Cox SD, Mann CM, Markham JL, et al. The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). J Appl Microbiol 2000;88:170-5.. View abstract.

De Groot A. C. and Weyland J. W. Systemic contact dermatitis from tea tree oil. Contact Dermatitis 1992;27(4):279-280. View abstract.

De Groot AC. Airborn allergic contact dermatitis from tea tree oil. Contact Dermatitis 1996;35:304-5. View abstract.

Del Beccaro MA. Melaleuca oil poisoning in a 17-month-old. Vet Hum Toxicol 1995;37:557-8. View abstract.

Dryden M. S., Dailly S. and Crouch M. A randomized, controlled trial of tea tree topical preparations versus a standard topical regimen for the clearance of MRSA colonization. J Hosp Infect 2004;56(4):283-286. View abstract.

Ebneyamin E, Mansouri P, Rajabi M, Qomi M, Asgharian R, Azizian Z. The efficacy and safety of permethrin 2.5% with tea tree oil gel on rosacea treatment: A double-blind, controlled clinical trial. J Cosmet Dermatol. 2019. View abstract.

Edmondson M, Newall N, Carville K, Smith J, Riley TV and Carson CF. Uncontrolled, open-label, pilot study of tea tree (Melaleuca alternifolia) oil solution in the decolonisation of methicillin-resistant Staphylococcus aureus positive wounds and its influence on wound healing. Int Wound J 2011;8(4):375-384. View abstract.

Elliott C. Tea tree oil poisoning. Med J Aust 1993;159:830-1. View abstract.

Elsom GF, Hyde D. Susceptibility of methicillin-resistant Staphylococcus aureus to tea tree oil and mupirocin. J Antimicrob Chemother 1999;43:427-8. View abstract.

Enshaieh S, Jooya A, Siadat AH, and Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian J Dermatol Venereol Leprol 2007;73(1):22-25. View abstract.

Ernst E. Adverse effects of herbal drugs in dermatology. Br J Dermatol 2000;143:923-9. View abstract.

Foster S, Tyler VE. Tyler’s Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999.

Gao YY, Di Pascuale MA, Elizondo A and Tseng SC. Clinical treatment of ocular demodecosis by lid scrub with tea tree oil. Cornea 2007;26(2):136-143. View abstract.

Greig JE, Thoo SL, Carson CF, Riley TV. Allergic contact dermatitis following use of a tea tree oil hand-wash not due to tea tree oil. Contact Dermatitis 1999;41:354-5. View abstract.

Hammer KA, Carson CF, Riley TV. In vitro activities of ketoconazole, econazole, miconazole, and Melaleuca alternifolia (tea tree) oil against Malassezia species. Antimicrob Agents Chemother 2000;44:467-9. View abstract.

Hammer KA, Carson CF, Riley TV. In-vitro activity of essential oils, in particular Melaleuca alternifolia (tea tree) oil and tea tree oil products, against Candida spp. J Antimicrob Chemother 1998;42:591-5. View abstract.

Hammer KA, Carson CF, Riley TV. Susceptibility of transient and commensal skin flora to the essential oil of Melaleuca alternifolia (tea tree oil). Am J Infect Control 1996;24:186-9.. View abstract.

Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal gynecomastia linked to lavender and tea tree oils. N Eng J Med 2007;356:479-85. View abstract.

Hugo Infante V, Maria Maia Campos P, Darvin M, et al. Cosmetic Formulations with Melaleuca alternifolia Essential Oil for the Improvement of Photoaged Skin: A Double-Blind, Randomized, Placebo-Controlled Clinical Study. Photochem Photobiol 2022. View abstract.

Hur MH, Park J, Maddock-Jennings W, Kim DO and Lee MS. Reduction of mouth malodour and volatile sulphur compounds in intensive care patients using an essential oil mouthwash. Phytother Res 2007;21(7):641-643. View abstract.

Jacobs MR, Hornfeldt CS. Melaleuca oil poisoning. J Toxicol Clin Toxicol 1994;32:461-4.. View abstract.

James PJ, Callander JT. Dipping and jetting with tea tree (Melaleuca alternifolia) oil formulations control lice (Bovicola ovis) on sheep. Vet Parasitol. 2012 Oct 26;189(2-4):338-43. View abstract.

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Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033-7. View abstract.

Joksimovic N, Spasovski G, Joksimovic V, et al. Efficacy and tolerability of hyaluronic acid, tea tree oil and methyl-sulfonyl-methane in a new gel medical device for treatment of haemorrhoids in a double-blind, placebo-controlled clinical trial. Updates Surg 2012;64:195-201. View abstract.

Kang HY, Na SS and Kim YK. [Effects of oral care with essential oil on improvement in oral health status of hospice patients]. J Korean Acad Nurs 2010;40(4):473-481. View abstract.

Khanna M, Qasem K, Sasseville D. Allergic contact dermatitis to tea tree oil with erythema multiforme-like id reaction. Am J Contact Dermat 2000;11:238-42.. View abstract.

Kheirkhah A, Casas V, Li W, Raju VK and Tseng SC. Corneal manifestations of ocular demodex infestation. Am J Ophthalmol 2007;143(5):743-749. View abstract.

Kim JH, Chun YS and Kim JC. Clinical and immunological responses in ocular demodecosis. J Korean Med Sci 2011;26(9):1231-1237. View abstract.

Knight TE, Hausen BM. Melaleuca oil (tea tree oil) dermatitis. J Am Acad Dermatol 1994;30:423-7.. View abstract.

Koh KJ, Pearce AL, Marshman G, et al. Tea tree oil reduces histamine-induced skin inflammation. Br J Dermatol 2002;147:1212-7.. View abstract.

Koo H, Kim TH, Kim KW, Wee SW, Chun YS, Kim JC. Ocular surface discomfort and Demodex: effect of tea tree oil eyelid scrub in Demodex blepharitis. J Korean Med Sci. 2012 Dec;27(12):1574-9. View abstract.

Kothiwale SV, Patwardhan V, Gandhi M, Sohoni R, Kumar A. A comparative study of antiplaque and antigingivitis effects of herbal mouthrinse containing tea tree oil, clove, and basil with commercially available essential oil mouthrinse. J Indian Soc Periodontol. 2014 May;18(3):316-20. View abstract.

Kwon HH, Yoon JY, Park SY, Min S, Suh DH. Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study. Dermatology. 2014;229(2):102-9. View abstract.

Lauriola MM, Sena P, De Bitonto A, Corazza M. Allergic contact dermatitis due to “therapeutic uses” of tea tree oil on the lips and toenails. Dermatitis. 2021;32(3):e40-e41. View abstract.

Liang L, Safran S, Gao Y, Sheha H, Raju VK and Tseng SC. Ocular demodicosis as a potential cause of pediatric blepharoconjunctivitis. Cornea 2010;29(12):1386-1391. View abstract.

Markum E and Baillie J. Combination of essential oil of Melaleuca alternifolia and iodine in the treatment of molluscum contagiosum in children. J Drugs Dermatol 2012;11(3):349-354. View abstract.

Martin KW, Ernst E. Herbal medicines for treatment of fungal infections: a systematic review of controlled clinical trials. Mycoses 2004;47:87-92. View abstract.

Martínez Campayo N, Goday Buján JJ, Fonseca Capdevila E. Allergic contact dermatitis due to tea tree oil. Actas Dermosifiliogr (Engl Ed). 2020;111(9):787-788. View abstract.

May J, Chan CH, King A, et al. Time-kill studies of tea tree oils on clinical isolates. J Antimicrob Chemother 2000;45:639-43. View abstract.

Mergen B, Arici C, Yildiz-Tas A, et al. Swabs Containing Tea Tree Oil and Chamomile Oil Versus Baby Shampoo in Patients With Seborrheic Blepharitis: A Double-Blind Randomized Clinical Trial. Eye Contact Lens 2021;47(11):604-610. View abstract.

Mohammadpour M, Maleki S, Khorrami-Nejad M. The effect of tea tree oil on dry eye treatment after phacoemulsification cataract surgery: A randomized clinical trial. Eur J Ophthalmol. 2019:1120672119867642. View abstract.

Morris MC, Donoghue A, Markowitz JA, Osterhoudt KC. Ingestion of tea tree oil (Melaleuca oil) by a 4-year-old boy. Pediatr Emerg Care 2003;19:169-71. View abstract.

Moss A. Tea tree oil poisoning. Med J Aust 1994;160:236. View abstract.

Najafi-Taher R, Jafarzadeh Kohneloo A, Eslami Farsani V, et al. A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial. Arch Dermatol Res 2022;314(7):673-679. View abstract.

Navarro-Triviño FJ, Prados-Carmona Á, Ruiz-Villaverde R. Systemic allergic contact dermatitis caused by tea tree oil in a cream for treatment of molluscum contagiosum. Contact Dermatitis 2022;87(3):285-287. View abstract.

Nelson RR. Selection of resistance to the essential oil of Melaleuca alternifolia in Staphylococcus aureus. J Antimicrob Chemother 2000;45:549-50. View abstract.

Pearce AL, Finlay-Jones JJ, Hart PH. Reduction of nickel-induced contact hypersensitivity reactions by topical tea tree oil in humans. Inflamm Res 2005;54:22-30. View abstract.

Ripari F, Cera A, Freda M, Zumbo G, Zara F, Vozza I. Tea tree oil versus chlorhexidine mouthwash in treatment of gingivitis: A pilot randomized, double blinded clinical trial. Eur J Dent. 2020;14(1):55-62. View abstract.

Robbers JE, Tyler VE. Tyler’s Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.

Rubel DM, Freeman S, Southwell IA. Tea tree oil allergy: what is the offending agent? Report of three cases of tea tree oil allergy and review of the literature. Australas J Dermatol 1998;39:244-7. View abstract.

Satchell AC, Saurajen A, Bell C and Barnetson RS. Treatment of dandruff with 5% tea tree oil shampoo. J Am Acad Dermatol 2002;47(6):852-855. View abstract.

Satchell AC, Saurajen A, Bell C, Barnetson RS. Treatment of interdigital tinea pedis with 25% and 50% tea tree oil solution: a randomized, placebo-controlled, blinded study. Australas J Dermatol 2002;43:175-8.. View abstract.

Savla K, Le JT, Pucker AD. Tea tree oil for Demodex blepharitis. Cochrane Database Syst Rev. 2020;6(6):CD013333. View abstract.

Saxer UP, Stauble A, Szabo SH and Menghini G. [Effect of mouthwashing with tea tree oil on plaque and inflammation]. Schweiz Monatsschr Zahnmed 2003;113(9):985-996. View abstract.

Seawright A. Comment: Tea tree oil poisoning. Med J Aust 1993;159:830-831.

Soukoulis, S. and Hirsch, R. The effects of a tea tree oil-containing gel on plaque and chronic gingivitis. Aust Dent J 2004;49(2):78-83. View abstract.

Srikumar KP, Bhagyashree BN, Srirangarajan S, Ravi RJ, Vinaya R. Efficacy of Melaleuca alternifolia and chlorhexidine mouth rinses in reducing oral malodor and Solobacterium moorei levels. A 1 week, randomized, double-blind, parallel study. Indian J Pharmacol 2022;54(2):77-83. View abstract.

Syed TA, Qureshi ZA, Ali SM, et al. Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream. Trop Med Int Health 1999;4:284-7. View abstract.

Tirabassi G, Giovannini L, Paggi F, Panin G, Panin F, Papa R, Boscaro M, Balercia G. Possible efficacy of Lavender and Tea tree oils in the treatment of young women affected by mild idiopathic hirsutism. J Endocrinol Invest. 2013 Jan;36(1):50-4. View abstract.

Tong MM, Altman PM, Barnetson RS. Tea tree oil in the treatment of tinea pedis. Australas J Dermatol 1992;33:145-9. View abstract.

Varma S, Blackford S, Statham BN, Blackwell A. Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. Contact Dermatitis 2000;42:309-10. View abstract.

Wallengren J. Tea tree oil attenuates experimental contact dermatitis. Arch Dermatol Res 2011;303(5):333-338. View abstract.

Zarei-Ghanavati S, Nooghabi MJ, Zamani G. Comparison of the Effect of Tea Tree Oil Shampoo With Regular Eyelid Shampoo in Meibomian Gland Dysfunction Treatment. Am J Ophthalmol 2021;229:45-51. View abstract.

Zhang SY, Robertson D. A study of tea tree oil ototoxicity. Audiol Neurootol 2000;5:64-8. View abstract.

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