What is the M365 Pill?
M365 is also known as M365 white pill.
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The DEA reclassified M365 to a Schedule II narcotic under the CSA (Controlled Substances Act) in 2014 due to reported patterns of misuse and abuse. Like all substances of this classification, M365 has limited medical applications combined with a strong potential for abuse and addiction.
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M365 is a white capsule-based prescription medication manufactured by Mallinckrodt Pharmaceuticals.
Physicians frequently prescribe M365 white pill to patients with back pain. The combination of both opioid and non-opioid painkillers can provide effective short-term relief from symptoms.
The medication contains:
- Acetaminophen (325mg)
- Hydrocodone (5mg)
M365 is an opioid classified as a narcotic analgesic combination drug. Its effectiveness as a painkiller leads to many people developing dependency and addiction. The hydrocodone content of these tablets is what makes them effective painkillers, but hydrocodone is also responsible for the strong abuse potential.
Medications Similar to the M365 Pill
Two common opioids similar to M365 pill are:
- Norco
- Vicodin
Norco
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Norco is a branded prescription medication manufactured by Watson Pharmaceuticals available in the following forms:
- Acetaminophen (325mg) and hydrocodone (5mg)
- Acetaminophen (325mg) and hydrocodone (7.5mg)
- Acetaminophen (325mg) and hydrocodone (10mg)
In the first of those forms, Norco contains the same ingredients as M365 pill.
Hydrocodone is a derivative of codeine heavily implicated in the opioid epidemic still unfolding in the United States. Hydrocodone binds to opioid receptors in the CNS (central nervous system) leading to a reduced perception of pain. The precise mechanism of action is still unknown.
The active ingredient is acetaminophen, the same ingredient found in OTC pain-relieving formulations like Tylenol. Acetaminophen also delivers analgesic effects through the CNS.
Vicodin
Vicodin is another opioid analgesic similar to M365 manufactured by Abbot Pharmaceuticals.
This combination medication is available in the following versions:
- Acetaminophen (300mg) and hydrocodone bitartrate (5mg)
- Acetaminophen (300mg) and hydrocodone bitartrate (7.5mg)
- Acetaminophen (300mg) and hydrocodone bitartrate (10mg)
The only difference between Norco and Vicodin is the higher acetaminophen content of Vicodin.
Why Are Opiate Analgesics Like M365 Prescribed?
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M365 pill, Norco, and Vicodin are indicated in the treatment of moderate and severe pain. These combination medications are normally only prescribed when all non-opioid options are exhausted.
If narcotic opiate painkillers like M365 are deemed essential, use should be as short-term as possible to prevent dependence forming.
What Are the Side Effects of M635 White Pill?
Even if you take M365 pill exactly as your doctor prescribes, any of the following M365 side effects can manifest:
- Mood changes
- Lightheadedness
- Dizziness
- Vomiting
- Nausea
- Drowsiness
- Anxiety
- Constipation
- GI issues
- Headaches
- Dry mouth
- Blurred vision
- Ringing in the ears
M365 misuse involves any use of the medication beyond the prescribed use. All the following are considered opioid misuse:
- Taking doses of M365 too early or too late.
- Increasing the dose of M365 to counter elevated pain levels.
- Using M365 recreationally for its euphoric effects.
Any form of opioid misuse can easily lead to abuse and addiction. Addiction to M365 is diagnosed as opioid use disorder in DSM-5-TR, the latest edition of Diagnostic and Statistical Manual of Mental Health Disorders published by APA (American Psychological Association).
Common side effects of long-term M365 abuse include:
- Dramatic mood swings
- Reduced motivation
- Exhaustion and fatigue
- Social withdrawal
- Irritability
- Agitation
- Nausea
- Vomiting
While abusive patterns of opioid use do not always lead to addiction, M365 abuse often leads to the development of opioid use disorder.
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