Brompheniramine-Pseudoephedrine-Dextromethorphan Risks, Warnings, and Complications

Brompheniramine-Pseudoephedrine-Dextromethorphan can cause serious medical problems in certain people. You may opt-out of taking this medicine if you are at a high risk of complications. Some of the risks of brompheniramine-pseudoephedrine-dextromethorphan use include:

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• ACCIDENTAL OVERDOSE: Antihistamines are present in many over-the-counter cold and allergy medications. As this medicine has an antihistamine (brompheniramine), it is easy to unintentionally consume many antihistamines. It can be hazardous to take more than one antihistamine at once. Overdosing on antihistamines can result in convulsions, hallucinations, and even death. These kinds of drugs carry a higher risk of overdose in infants and young children. Always confirm the safety of using additional cold and allergy medications with this medication with your doctor or pharmacist first.

• DROWSINESS: Brompheniramine-Pseudoephedrine-Dextromethorphan can make you drowsy and affect your ability to think clearly. The risk is higher in people who consume alcohol or are taking other medications that can cause drowsiness, such as an opioid pain reliever, benzodiazepine (tranquilizer), or sleeping pill. Be careful while doing anything that requires your complete attention, such as driving or operating machinery, until you know how this drug affects you.

• DANGEROUS DRUG INTERACTION: Do not use brompheniramine-pseudoephedrine-dextromethorphan if you are currently consuming or recently consumed within the past 14 days monoamine oxidase inhibitors (MAO) drugs, such as selegiline, phenelzine, or tranylcypromine. When used with MAO inhibitors, brompheniramine-pseudoephedrine-dextromethorphan can result in hazardous changes in your blood pressure.

• HYPERACTIVITY IN CHILDREN: Brompheniramine-pseudoephedrine-dextromethorphan typically makes adults sleepy; however, it can have the reverse effect on children and make them hyper and excited. Speak with your child’s doctor to discuss alternative options if they are experiencing problems sleeping after starting this medicine.

• SEROTONIN SYNDROME: Too much serotonin in the brain causes the rare but potentially fatal illness known as serotonin syndrome. If you combine brompheniramine-pseudoephedrine-dextromethorphan with other drugs that influence serotonin levels (such as lithium, some Parkinson’s disease treatments, or antidepressants), your risk increases. Before beginning treatment with brompheniramine-pseudoephedrine-dextromethorphan, inform your pharmacist of all prescription and over-the-counter medications you are currently taking so they may check for potential interactions. A rapid heartbeat, sweating, muscle stiffness or spasms, fever, and confusion are signs of an excess of serotonin. If you have any of these symptoms, tell your doctor or get emergency medical help.

Precautions Before Starting Brompheniramine-Pseudoephedrine-Dextromethorphan

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Tell your doctor or pharmacist if you have ever had an allergic reaction to brompheniramine, pseudoephedrine, dextromethorphan, or other medications. Your pharmacy can give you a list of ingredients.

Give your doctor a complete medical history. Brompheniramine-Pseudoephedrine-Dextromethorphan can worsen your condition and cause serious side effects if you suffer from health conditions such as narrow-angle glaucoma, difficulty urinating (due to an enlarged prostate gland), diabetes, high blood pressure, heart disease, thyroid disorder, liver or kidney disease, lung or breathing problems (asthma, chronic bronchitis, emphysema), seizures, stomach ulcer, a blockage in your digestive tract (stomach or intestines), if you smoke or if you have a cough that occurs with a large amount of phlegm or mucus.

Give your doctor and pharmacist a complete list of your medications, including prescription drugs, over-the-counter medicines, vitamins, supplements, and herbal products. This can help avoid possible drug interactions between brompheniramine-pseudoephedrine-dextromethorphan and your other medications.

If you are an older adult more than 65 years of age, discuss the risks and benefits of taking brompheniramine-pseudoephedrine-dextromethorphan with your doctor.

Tell your doctor if you are pregnant, could be pregnant, are planning a pregnancy, or are breastfeeding.

Precautions During Use of Brompheniramine-Pseudoephedrine-Dextromethorphan

Check in with your doctor regularly to see how you’re doing. If your symptoms do not begin to improve after 7 days, or if you have a fever, skin rash, or headaches, seek emergency medical help.

Brompheniramine-Pseudoephedrine-Dextromethorphan can make you drowsy and dizzy the morning after use. It can affect your mental alertness and make you more likely to fall. Do not drive, operate machinery, or do anything that requires alertness until you know how brompheniramine-pseudoephedrine-dextromethorphan

affects you.

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Do not drink alcohol while taking brompheniramine-pseudoephedrine-dextromethorphan. Alcohol can make the side effects of this medicine worse.

Inform your doctor in advance if you need surgery or testing if you’ve recently taken this medication.

Call your doctor if you become pregnant while taking Xyzal. Do not take this medicine while breastfeeding.

Your mouth can become dry. Drinking lots of water, nibbling on hard candies, and chewing sugarless gum may be helpful. If the issue persists or becomes serious, call your doctor.

Brompheniramine-Pseudoephedrine-Dextromethorphan can also cause dry eyes and blurred vision. It’s possible to experience some discomfort if you use contact lenses. Lubricant drops could be useful. If the issue persists or is serious, consult your eye doctor.

Brompheniramine-Pseudoephedrine-Dextromethorphan Drug Interactions

Certain other drugs can affect how brompheniramine-pseudoephedrine-dextromethorphan works. Possible interactions between brompheniramine-pseudoephedrine-dextromethorphan and other medicines can increase the risk of severe adverse effects. Your doctor may change the dose of your medications or monitor you carefully for side effects if there are known interactions between brompheniramine-pseudoephedrine-dextromethorphan and your other medicines.

The following medications can have possible interactions with brompheniramine-pseudoephedrine-dextromethorphan:

• Monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate)
• Muscle relaxant medications
• Narcotic medications for pain
• Alcohol and other Central nervous system (CNS) depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.)
• Medicines for blood pressure
• Certain medicines for seizures like phenobarbital, primidone
• Other cold or allergy medicines
• Atropine
• Certain medicines for Parkinson’s disease like benztropine, trihexyphenidyl
• Bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva)
• Certain medicines for travel sickness like scopolamine
• Irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine)
• Ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
• Linezolid or methylene blue

The above list may not include all the possible interactions of brompheniramine-pseudoephedrine-dextromethorphan. Give your doctor or pharmacist a complete list of your medications, including prescription drugs, over-the-counter medicines, dietary supplements, and herbal remedies. Also, tell your healthcare provider if you smoke, drink alcohol, or use recreational drugs because some of these substances can cause serious health complications when used with prescription and over-the-counter medicines.

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