What causes globus pharyngeus?
The most common cause of globus sensation is acid reflux (conditions like GERD and LPR). When stomach acid flows backward, it can irritate the lining of your food pipe (esophagus) and make your throat feel tight.
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In other cases, throat tension can make it feel like there’s something stuck. Allergies, infections and anxiety can all cause muscle tension in this area.
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Other globus sensation causes include:
- Cervical spine conditions. Structural changes to the upper part of your spine (neck) may press on nearby muscles or nerves and cause globus sensation in your throat.
- Inflammation. Swollen tissues near your throat, tonsils or sinuses can cause globus sensation.
- Postnasal drip. Excess mucus from your nose and sinuses can build up and slide down the back of your throat. This can trigger globus sensation.
- Smoking and vaping. Inhaling tobacco smoke or nicotine vapor can irritate the tissues in your throat and cause globus.
- Stress and anxiety. Holding back strong emotions, like grief, can make it feel like there’s a lump in your throat.
- Thyroid disease. An enlarged thyroid or thyroid nodules can press on surrounding structures and cause globus sensation.
- Vocal strain. Using your voice for extended periods of time can trigger muscle tension and globus sensation.
What can globus sensation be mistaken for?
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Sometimes, globus sensation can look and act like other conditions. Examples include:
- Esophageal spasms: The muscles around your esophagus contract abnormally.
- Esophageal webs: Thin folds of tissue that form along your esophagus and make swallowing more difficult.
- Myasthenia gravis: An autoimmune disease that disrupts communication between your nerves and muscles. It can cause weakness in your throat muscles.
- Myositis: A rare autoimmune disease that causes inflammation and weakness in your muscle fibers.
- Myotonic dystrophy: A rare form of muscular dystrophy that prevents you from relaxing your muscles at will.
- Tumors in the neck or upper chest: Tumors in these areas can press on surrounding structures and cause tightness in your throat.
Be sure to see a healthcare provider if your symptoms don’t go away. They can determine whether you have globus or another condition.
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